Genius1111 Posted April 11, 2022 Posted April 11, 2022 (edited) Updated Nov 30 2021 Source: Tracking SARS-CoV-2 variants (who.int) Working definition: A SARS-CoV-2 variant that meets the definition of a VOI (see below) and, through a comparative assessment, has been demonstrated to be associated with one or more of the following changes at a degree of global public health significance: Increase in transmissibility or detrimental change in COVID-19 epidemiology; OR Increase in virulence or change in clinical disease presentation; OR Decrease in effectiveness of public health and social measures or available diagnostics, vaccines, therapeutics. Currently designated Variants of Concern (VOCs)+: WHO label Pango lineage• GISAID clade Nextstrain clade Additional amino acid changes monitored° Earliest documented samples Date of designation Alpha B.1.1.7 GRY 20I (V1) +S:484K +S:452R United Kingdom, Sep-2020 18-Dec-2020 Beta B.1.351 GH/501Y.V2 20H (V2) +S:L18F South Africa, May-2020 18-Dec-2020 Gamma P.1 GR/501Y.V3 20J (V3) +S:681H Brazil, Nov-2020 11-Jan-2021 Delta B.1.617.2 G/478K.V1 21A, 21I, 21J +S:417N +S:484K India, Oct-2020 VOI: 4-Apr-2021 VOC: 11-May-2021 Omicron* B.1.1.529 GR/484A 21K - Multiple countries, Nov-2021 VUM: 24-Nov-2021 VOC: 26-Nov-2021 • Includes all descendent lineages. See the cov-lineages.org and the Pango network websites for further details. * See TAG-VE statement issued on 26 November 2021 ° Only found in a subset of sequences *Notable spike (S) amino acid changes under monitoring, which are currently reported in a minority of sequenced samples. Working definition A SARS-CoV-2 variant : with genetic changes that are predicted or known to affect virus characteristics such as transmissibility, disease severity, immune escape, diagnostic or therapeutic escape; AND Identified to cause significant community transmission or multiple COVID-19 clusters, in multiple countries with increasing relative prevalence alongside increasing number of cases over time, or other apparent epidemiological impacts to suggest an emerging risk to global public health. Currently designated Variants of Interest: WHO label Pango lineage* GISAID clade Nextstrain clade Earliest documented samples Date of designation Lambda C.37 GR/452Q.V1 21G Peru, Dec-2020 14-Jun-2021 Mu B.1.621 GH 21H Colombia, Jan-2021 30-Aug-2021 The journey so far... (as of Jul 08 2022) Average rise in neutralizing antibody levels: Live Science Pfizer-BioNTech Booster Moderna Booster Johnson & Johnson Booster Two doses Pfizer-BioNTech Initially 20x 31.7x 12.5x Two doses Moderna Initially 11.5x 10.2x 6.2x One dose Johnson & Johnson Initially 35.1x 75.9x 4.2x ____________________________________________________________________________________________________ Long-terms effects of COVID-19 ("Long COVID") More than 50 long-term effects of COVID-19: a systematic review and meta-analysis | Scientific Reports (nature.com) ___________________________________________________________________________________________ Information added on Jan 25 2022 Statement on Therapies for High-Risk, Nonhospitalized Patients | COVID-19 Treatment Guidelines (nih.gov) Mixing and matching vaccines Information accurate as of Nov 2021 Note: Always check with a medical professional first if you have any doubts on the vaccines that you are going to get _________________________________________________________ Let's support one another in these difficult times! _________________________________________________________ Masks 4 All https://masks4all.co/ _________________________________________________________ [My original post on Jan 09 2020] https://www.google.com/amp/s/time.com/5759289/wuhan-pneumonia-outbreak-disease/%3famp=true How serious is the pneumonia outbreak? According to Wuhan's health bureau, 59 patients have been diagnosed with the virus, including seven in critical condition as of Sunday. Some of the patients operated stalls at the seafood market. All of the patients are in quarantine, and 163 people who had been in close contact with them have been placed under medical observation. The World Health Organization says symptoms include fever and difficulty breathing. How fast is it spreading? The first case was discovered in Wuhan on Dec. 12, the city's health bureau says. On Monday, authorities in Hong Kong reported that six more patients were found to have fever or respiratory symptoms after returning from Wuhan, bringing the number of cases in the city to 30. Edited August 24 by Genius1111
Ms. Togekiss Posted April 14, 2022 Posted April 14, 2022 omicron keeps trying it but it looks like every new version keeps flopping
Genius1111 Posted April 14, 2022 Author Posted April 14, 2022 My 2nd post on Jan 12 2020 is gone! (But I am still the OP, so )
Cloröx Posted April 14, 2022 Posted April 14, 2022 15 minutes ago, Ms. Togekiss said: omicron keeps trying it but it looks like every new version keeps flopping Too soon to tell, the playlists will ensure longevity
Genius1111 Posted April 14, 2022 Author Posted April 14, 2022 (edited) It has been 835 days since the WHO was notified of this strange new coronavirus (on Dec 31 2019). Edited April 14, 2022 by Genius1111
Chemist Posted April 14, 2022 Posted April 14, 2022 Aww the old thread was so iconic, especially at the beginning of the pandemic. It had some insane and intense moments
Genius1111 Posted April 14, 2022 Author Posted April 14, 2022 A cute and light-hearted video on COVID antibodies featuring Thai celebrities. (Also posted in the BL drama base thread.) In Thailand, having four shots is the norm, it seems. (They had to rely on Sinovac/Sinopharm/AZ in the beginning.) Bonus: Jumpol Adulkittip0rn's cute face and his reactions to needles.
frenchyisback Posted April 14, 2022 Posted April 14, 2022 1 hour ago, Jotham said: The new Mao. We love to see the CCP crash. Poor Chinese citizen. Here come the next great famine with that kinda dumb stubborn anti-science leader.
Jude Posted April 14, 2022 Posted April 14, 2022 Glad this sh*t is over in many countries including ours. Sorry for those who are still having surges and lockdowns.
Chemist Posted April 14, 2022 Posted April 14, 2022 It's going to take at least another month to get back to zero I don't think the people in Shanghai are going to bear that long
truthteller Posted April 14, 2022 Posted April 14, 2022 (edited) 5 hours ago, frenchyisback said: The new Mao. We love to see the CCP crash. Poor Chinese citizen. Here come the next great famine with that kinda dumb stubborn anti-science leader. i wonder how they are gonna do with the "permanent COVID positive" cases there Summary: Only confirmation from isolation centre can be considered as proof for recovery. No self-testing is allowed and no test will be offered to people who refuse to go to "isolation centre". If a person refuses to go to "isolation centre" even test results are negative, that person will be considered as POSITIVE case permanently and the health code will forever be shown as POSITIVE The whole community / residential area will be locked down if any one of the resident refuses to go to "isolation centre" Edited April 14, 2022 by truthteller
Genius1111 Posted April 14, 2022 Author Posted April 14, 2022 Quote Those who received the Sinovac vaccine were 4.59 times more likely to have severe COVID-19 compared to those who received the Pfizer-BioNTech vaccine. They were also 2.37 times more likely to be infected, compared to those who took the Pfizer-BioNTech vaccine. The findings also suggest that the Moderna vaccine is more effective at preventing severe disease than the Pfizer-BioNTech vaccine. Those who took the Moderna were found to be less than half (0.42) times as likely to develop severe COVID-19 than Pfizer-BioNTech recipients, and they are also less likely to be infected. Citing a report from the US Centers for Disease Control and Prevention, the higher effectiveness of the Moderna vaccine was likely because of the higher mRNA content in the Moderna vaccine and longer time interval between the jabs. Quote A total of 107,220 of those vaccinated were confirmed by polymerase chain reaction (PCR) tests to have COVID-19 over the study period, and 644 developed severe disease. While the study was based on “comprehensive national data”, the team said there were “several limitations”. This included the “residual confounding” from comorbidities as well as factors that influence a person’s choice of vaccine or risk of exposure. There were also asymptomatic cases who did not see a doctor and were not recorded as cases.
Vermillion Posted April 14, 2022 Posted April 14, 2022 My last post before the forum reset was on the Dept Head of UCSF saying for the U.S. to get mRNA boosters every 2 months until better boosters are developed for Omicron/BA2 and we get a higher Paxlovid supply. I'd try it if the pharmacy allowed it but they've been strict with attempts from friends I know Also Chise already clarified that XE is NOT a new VOC. Of course it's still worth posting about and monitoring, but it's important to clarify that.
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