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  1. Updated Nov 30 2021 Source: Tracking SARS-CoV-2 variants (who.int) Working definition: A SARS-CoV-2 variant that meets the definition of a VOI (see below) and, through a comparative assessment, has been demonstrated to be associated with one or more of the following changes at a degree of global public health significance: Increase in transmissibility or detrimental change in COVID-19 epidemiology; OR Increase in virulence or change in clinical disease presentation; OR Decrease in effectiveness of public health and social measures or available diagnostics, vaccines, therapeutics. Currently designated Variants of Concern (VOCs)+: WHO label Pango lineage• GISAID clade Nextstrain clade Additional amino acid changes monitored° Earliest documented samples Date of designation Alpha B.1.1.7 GRY 20I (V1) +S:484K +S:452R United Kingdom, Sep-2020 18-Dec-2020 Beta B.1.351 GH/501Y.V2 20H (V2) +S:L18F South Africa, May-2020 18-Dec-2020 Gamma P.1 GR/501Y.V3 20J (V3) +S:681H Brazil, Nov-2020 11-Jan-2021 Delta B.1.617.2 G/478K.V1 21A, 21I, 21J +S:417N +S:484K India, Oct-2020 VOI: 4-Apr-2021 VOC: 11-May-2021 Omicron* B.1.1.529 GR/484A 21K - Multiple countries, Nov-2021 VUM: 24-Nov-2021 VOC: 26-Nov-2021 • Includes all descendent lineages. See the cov-lineages.org and the Pango network websites for further details. * See TAG-VE statement issued on 26 November 2021 ° Only found in a subset of sequences *Notable spike (S) amino acid changes under monitoring, which are currently reported in a minority of sequenced samples. Working definition A SARS-CoV-2 variant : with genetic changes that are predicted or known to affect virus characteristics such as transmissibility, disease severity, immune escape, diagnostic or therapeutic escape; AND Identified to cause significant community transmission or multiple COVID-19 clusters, in multiple countries with increasing relative prevalence alongside increasing number of cases over time, or other apparent epidemiological impacts to suggest an emerging risk to global public health. Currently designated Variants of Interest: WHO label Pango lineage* GISAID clade Nextstrain clade Earliest documented samples Date of designation Lambda C.37 GR/452Q.V1 21G Peru, Dec-2020 14-Jun-2021 Mu B.1.621 GH 21H Colombia, Jan-2021 30-Aug-2021 Average rise in neutralizing antibody levels: Live Science Pfizer-BioNTech Booster Moderna Booster Johnson & Johnson Booster Two doses Pfizer-BioNTech Initially 20x 31.7x 12.5x Two doses Moderna Initially 11.5x 10.2x 6.2x One dose Johnson & Johnson Initially 35.1x 75.9x 4.2x ____________________________________________________________________________________________________ Long-terms effects of COVID-19 ("Long COVID") More than 50 long-term effects of COVID-19: a systematic review and meta-analysis | Scientific Reports (nature.com) ___________________________________________________________________________________________ Mixing and matching vaccines Information accurate as of Nov 2021 Note: Always check with a medical professional first if you have any doubts on the vaccines that you are going to get _________________________________________________________ Let's support one another in these difficult times! _________________________________________________________ Masks 4 All https://masks4all.co/ _________________________________________________________ [My original post on Jan 09 2020] https://www.google.com/amp/s/time.com/5759289/wuhan-pneumonia-outbreak-disease/%3famp=true How serious is the pneumonia outbreak? According to Wuhan’s health bureau, 59 patients have been diagnosed with the virus, including seven in critical condition as of Sunday. Some of the patients operated stalls at the seafood market. All of the patients are in quarantine, and 163 people who had been in close contact with them have been placed under medical observation. The World Health Organization says symptoms include fever and difficulty breathing. How fast is it spreading? The first case was discovered in Wuhan on Dec. 12, the city’s health bureau says. On Monday, authorities in Hong Kong reported that six more patients were found to have fever or respiratory symptoms after returning from Wuhan, bringing the number of cases in the city to 30.
  2. khalyan

    US Politics 🇺🇸

    Hey everyone! With permission of ATRL admins, I can announce this as the new official home for discussions related to US politics for the time being! 2020 US Presidential Election (op will be under construction for a little bit) Please, remember to be courteous to other members because not everyone will see every issue in the same way. Flame bait, name calling, trolling, and other disruptions will not be tolerated. Friendly debate is welcome and encouraged
  3. Mariya Takeuchi

    Hero rat that detected landmines dies

    Magawa the 'hero rat', who was given a medal for detecting landmines in Cambodia, dies aged eight During his incredible career, African giant pouched rat sniffed out more than 100 landmines and other explosives. He also became the first rat to be awarded the UK's PDSA Gold Medal, which is the animal equivalent of the George Cross. Magawa, the landmine-detecting "hero rat", has died at the age of eight. The African giant pouched rat, who sniffed out landmines and other explosives in Cambodia, was one of the most successful rodents trained by Belgian charity APOPO. During his five-year career, he managed to clear more than 225,000sq m of land - the equivalent of about 31 football pitches - and discovered 71 landmines and 38 items of unexploded ordnance, the charity previously said. In 2020, he became the first rat to be awarded the PDSA Gold Medal, the animal equivalent of the George Cross which recognises acts of heroism by British citizens and military personnel. A year later Magawa, also known as a "hero rat", decided to take a back seat from the action and retired, with his baton at the charity being taken up by another rodent named Ronin. APOPO said Magawa died "peacefully" at the weekend after being in "good health" and spending his last few days "playing with his usual enthusiasm". Since 2000, the organisation has worked to train and breed landmine detection rats at its operational headquarters at Sokoine University of Agriculture in Tanzania - where Magawa was born and developed his impressive nose for explosives. At the age of three, he moved to Siem Reap in Cambodia and began his work. A lasting legacy https://news.sky.com/story/magawa-the-hero-rat-who-was-given-a-medal-for-detecting-landmines-in-cambodia-dies-aged-eight-12513667
  4. I was just gonna post this in the HIV thread but couldn't find it as I know people are tired of hearing about new research on this topic without much progress.
  5. Snorlax still that main Pokemon girl
  6. https://www.timesofisrael.com/new-citizenship-law-advances-months-after-ban-on-palestinian-spouses-lapsed/
  7. Canada PM called them “Idiots”. Airlines are refusing to fly them back from Mexico for breaking Covid safety protocols. CBC News
  8. I don't get how they tested positive and then managed to be out and about. The managed isolation facilities have the army posted outdoors. God help us.
  9. hurricane326

    World's oldest person turns 119!

    Kane Tanaka, of Fukuoka, Japan, turned 119 on January 2, 2022. The third oldest person ever, she has 98 more days to go to become second, meaning she would beat Sarah Knauss, of Allentown, Pennsylvania, who died in 1999. She has stated her goal is to live to 120. One more year! https://en.wikipedia.org/wiki/Kane_Tanaka
  10. First they love you then they switch.
  11. hurricane326

    Woman uses Alexa for ha revenge

    An oldie but a goodie! Would you do the same? https://www.insider.com/woman-jailed-after-using-amazon-alexa-threaten-exs-new-partner-2021-10 Phillipa Copleston-Warren, 46, from London, used the device to blare "get the whore out" at her former partner's home in Lincolnshire She also threatened the couple by using a connected app to switch their bedside light on and off. The unnamed victim was unable to use his Facebook or Match.com accounts. Copleston-Warren was also able to access and download a naked picture of her ex, sharing it widely onto his social media with the caption "do I look fat??? She was spared a three months prison sentence
  12. Update to this thread by @heckinglovato from a few days ago.
  13. LuLuDrops

    France Bans “Conversion Therapy”

    The gay slays this month
  14. Just happened in the past hour across several states. Mayfield, Kentucky and Bowling Green, KY hit hard. The roof of a candle factory collapsed and killed, apparently, at least 50 people from that alone. A car plant was on fire with people trapped inside, and an Amazon warehouse roof collapsed killing 4 in Illinois.
  15. Dozens of people were feared dead and communities across the Midwest and southern United States were left scrambling to assess the damage on Saturday morning after a string of unseasonably powerful storms and tornadoes swept across five states overnight. Kentucky’s governor said that at least 50 had been killed in a tornado’s path of over 200 miles, and that the state’s death toll was likely to increase to more than 70 in the coming hours. At least five states were hit by tornadoes on Friday night, including Arkansas, Illinois, Kentucky, Missouri and Tennessee, said Bill Bunting, the operations chief at the Storm Prediction Center, part of the National Weather Service. https://www.nytimes.com/live/2021/12/11/us/tornadoes-storms-amazon To put this in historical perspective, the last tornado to cause this many deaths (the toll could easily reach 100) was in Joplin, Missouri in 2011, where 157 died. Before that there was Worcester, Massachusetts (94 dead), and Beecher, Michigan (116 dead) both in June 1953. This is absolutely historic for the 21st century. In addition, this tornado family traveled for over 200 miles, rivaling the 1925 Tri-State Tornado (695 dead - deadliest in US history) for path length RIP to all the victims :(
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