Animal Experimenter frauds Data To Brain Injure Piglets

[GraceRandolph]

Last December, in the wake of animal cruelty allegations against Elon Musk’s brain chip startup Neuralink, Vox’s Kenny Torrella wrote about a concept he called “the moral math of animal testing”: the view held by many people that trading some amount of animal suffering is worth it if it can save enough human lives by advancing medicine.

 

Experimentation on live animals is a divisive, morally charged subject. Slightly more than half of Americans saythey oppose using animals in scientific research, according to a 2018 Pew survey, but it depends a lot on how you phrase the question and who is asking. When asked by the biomedical industry whether they support “the humane use of animals” to develop “lifesaving medicines,” many more people say they do, or aren’t sure. These gaps reflect the public’s lack of understanding of how vivisection works in general: Most people don’t know whether animal testing is humane, effective, or necessary, nor do they always know how to define those terms.

Not everyone will agree with my view of vivisection, which is that it’s unjustifiable in nearly all circumstances. But I would think most people will agree that animal experiments should have to clear an especially high bar — that they have to be truly necessary for saving human lives and irreplaceable with non-animal methods.

 

That is, unfortunately, not how animal testing in the US works at all. Scientists harm and kill animals for all sorts of studies that have nothing to do with saving human lives. Researchers at Oregon Health & Science University, for example, have forced prairie voles to drink alcohol to test whether it makes them cheat on their partners. A Harvard neuroscientist recently came under fire for separating caged mother monkeys from their babies and giving them surrogate stuffed animals to bond with, thus demonstrating, she wrote in a top scientific journal, that “infant/mother bonds may be triggered by soft touch.”

 

Animal experimentation is also not immune to outright fraud, a problem that’s “disturbingly common” in science, as Vox’s Kelsey Piper wrote in June. Last week, federal investigators found that William Armstead, a former professor at the University of Pennsylvania’s medical school, had faked the results of multiple federally funded studies that involved cutting open piglets’ skulls and inducing brain injuries. The studies were meant to test drugs for treating brain injuries in humans. (Armstead left the university while he was under investigation for this misconduct.)

 

Some of Armstead’s fabrications, which included relabeling results from past studies as new ones, appear designed to make a drug his team was studying look more effective, Ivan Oransky, co-founder of Retraction Watch — a blog that tracks retractions of scientific papers — told the Philadelphia Inquirer last week. Armstead’s team doctored 51 scientific figures across five published studies, three federal grant applications, and other documents. The faked data renders the research useless; it’s now been retracted from journals and can’t be incorporated into future work. “A bunch of pigs were subjected to some pretty terrible conditions for no reason,” Oransky told the Inquirer.

Armstead now faces a seven-year ban on conducting federally funded research, a penalty that’s relatively rare in its severity. But his case isn’t an isolated one.

Last year, a pivotal 2006 mouse study, which had been thought to shed light on the pathology of Alzheimer’s disease and shaped years of federally funded research, was credibly accused of being fraudulent and remains under investigation.

Also last year, federal officials found Deepak Kaushal, then-head of the federally funded Southwest National Primate Research Center in San Antonio, to have falsified results in a published study of a tuberculosis treatment tested on monkeys, and used those results in two NIH grant applications. Kaushal was placed under a one-year supervision period — the lightest imaginable slap on the wrist — with no lasting consequences for his ability to experiment on animals. He also, according to initial reports, got to keep his job as director of the lab. After criticism from some in the research community and animal advocates, he was later demoted from that position; it’s unclear whether he’ll be reinstated after his supervision period.

 

All these revelations should raise alarms about how misconduct is handled in research involving animal testing. When a top primate researcher is allowed to keep experimenting on monkeys after falsifying data, it sends a message to everyone in the research community that recklessly handling animal experiments, while temporarily embarrassing, may not be that big a deal.

[wehan6]

[Vixen Eyes]

poor things!

 

but also

[Illuminati]

Electric experiment on him

 

[GraceRandolph]

1 hour ago, wehan6 said:

The fact that this man is only banned from experimenting on animals for 7 years.

[Headlock]

4 hours ago, Juanny said:

Many, many studies in science have been faked or datasets subjected to generous experimental post-hoc elimination criteria to magnify group differences or trends in otherwise statistically insignificant data. Often the studies are so niche and require such specialized tools, skills, research questions, and equipment that they are never replicated but are the basis of many other studies. Science is a political institution that asks questions that are most likely to yield a result, not ones that are most likely to yield an understanding of the critical phenomena that need to be studied. Risky experiments. 
 

The issue is institutional and embedded in the way science is funded and the political games that are played in throwing research AND funding around. There is so little accountability and so little reason to perform good, high quality science. It needs to change if we want to properly advance our knowledge in a way that benefits humanity.

God if I could like this twice I would. Having been involved in basic science research for many years previously, that world is so toxic and just a rat race (pun intended) of a dwindling amount of PIs fighting over smaller and smaller amounts of funding. It’s basically become an old boy’s club where institutional titans get all of the grants despite never publishing actual groundbreaking research, while new and fresh minds and perspectives get thrown to the wayside and quickly become jaded.

[Breathe On Moi]

sounds like an upcoming AHS episode