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[Day 1042] ūüė∑ COVID-19 | 637.696M cases 6.606M dead | Nov 05 +226K cases / 543 dead


Genius1111
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Updated Nov 30 2021

 

Source: Tracking SARS-CoV-2 variants (who.int)

 

 

Working definition:

A SARS-CoV-2 variant that meets the definition of a VOI (see below) and, through a comparative assessment, has been demonstrated to be associated with one or more of the following changes at a degree of global public health significance: 

  • Increase in transmissibility or detrimental change in COVID-19 epidemiology; OR
  • Increase in virulence or change in clinical disease presentation; OR
  • Decrease in effectiveness of public health and social measures or available diagnostics, vaccines, therapeutics.¬†¬†

 

 

Currently designated Variants of Concern (VOCs)+:

WHO label 

Pango  
lineage‚ÄĘ
GISAID clade Nextstrain¬†clade¬† Additional¬†amino acid changes¬†monitored¬į Earliest documented¬†¬†
samples 
Date of designation 

Alpha 

B.1.1.7 

GRY

20I (V1) 

+S:484K
+S:452R

United Kingdom,  
Sep-2020 

18-Dec-2020

Beta 

B.1.351 

GH/501Y.V2  20H (V2) +S:L18F South Africa,  
May-2020 
18-Dec-2020
Gamma 

P.1 

GR/501Y.V3  20J (V3) +S:681H Brazil,  
Nov-2020 
11-Jan-2021
Delta 

B.1.617.2

G/478K.V1  21A, 21I, 21J

+S:417N

+S:484K

India,  
Oct-2020 
VOI: 4-Apr-2021 
VOC: 11-May-2021
Omicron* B.1.1.529 GR/484A 21K - Multiple countries, Nov-2021

VUM: 24-Nov-2021

VOC: 26-Nov-2021

‚ÄĘ Includes all descendent lineages. See the¬†cov-lineages.org¬†and the¬†Pango network¬†websites for further details.

* See TAG-VE statement issued on 26 November 2021

¬į Only found in a subset of sequences

 


*Notable spike (S) amino acid changes under monitoring, which are currently reported in a minority of sequenced samples.

 

 

 

Working definition

A SARS-CoV-2 variant : 

  • with¬†genetic changes that are predicted or known to affect virus characteristics such as transmissibility, disease severity, immune escape, diagnostic or therapeutic escape; AND¬†
  • Identified to cause significant community transmission or multiple COVID-19 clusters, in multiple countries with increasing relative prevalence alongside increasing number of cases over time, or other apparent epidemiological impacts to suggest an emerging risk to global public health.¬†¬†

 

Currently designated Variants of Interest:

WHO label  Pango  
lineage*
GISAID clade Nextstrain  
clade 
Earliest documented  
samples 
Date of designation 
           

Lambda

C.37

GR/452Q.V1

21G

Peru, Dec-2020

14-Jun-2021
Mu B.1.621 GH 21H Colombia, Jan-2021 30-Aug-2021

 

 

 

 

 

The journey so far... (as of Jul 08 2022)

 

 

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Average rise in neutralizing antibody levels: Live Science

  Pfizer-BioNTech Booster Moderna Booster Johnson & Johnson Booster
Two doses Pfizer-BioNTech Initially 20x 31.7x 12.5x
Two doses Moderna Initially 11.5x 10.2x 6.2x
One dose Johnson & Johnson Initially 35.1x 75.9x 4.2x

 

____________________________________________________________________________________________________

 

Long-terms effects of COVID-19 ("Long COVID")

 

More than 50 long-term effects of COVID-19: a systematic review and meta-analysis | Scientific Reports (nature.com)

 

figure2

 

 

___________________________________________________________________________________________

 

Information added on Jan 25 2022

 

Statement on Therapies for High-Risk, Nonhospitalized Patients | COVID-19 Treatment Guidelines (nih.gov)

 

FIWs54FXwAErjz5?format=jpg&name=small

 

 

 

Mixing and matching vaccines

Information accurate as of Nov 2021

Note: Always check with a medical professional first if you have any doubts on the vaccines that you are going to get

 

 

_________________________________________________________

 

Let's support one another in these difficult times!

 

 

_________________________________________________________

 

Masks 4 All

 

https://masks4all.co/

 

 

 

 

 

_________________________________________________________

 

[My original post on Jan 09 2020]

 

https://www.google.com/amp/s/time.com/5759289/wuhan-pneumonia-outbreak-disease/%3famp=true

 

 

How serious is the pneumonia outbreak?

 

According to Wuhan’s health bureau, 59 patients have been diagnosed with the virus, including seven in critical condition as of Sunday. Some of the patients operated stalls at the seafood market. All of the patients are in quarantine, and 163 people who had been in close contact with them have been placed under medical observation. The World Health Organization says symptoms include fever and difficulty breathing.

 

How fast is it spreading?

 

The first case was discovered in Wuhan on Dec. 12, the city’s health bureau says. On Monday, authorities in Hong Kong reported that six more patients were found to have fever or respiratory symptoms after returning from Wuhan, bringing the number of cases in the city to 30.

Edited by Genius1111
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Now we back to square one :gaycat6:

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BA.4 and BA.5 dropping while we were gone :jonny:

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omicron keeps trying it but it looks like every new version keeps flopping

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My 2nd post on Jan 12 2020 is gone!

 

(But I am still the OP, so :gaycat5:)

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15 minutes ago, Ms. Togekiss said:

omicron keeps trying it but it looks like every new version keeps flopping

Too soon to tell, the playlists will ensure longevity

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Posted (edited)

It has been 835 days since the WHO was notified of this strange new coronavirus (on Dec 31 2019). :gaycat6:

Edited by Genius1111
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835 days of hell :frown:

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Aww the old thread was so iconic, especially at the beginning of the pandemic. It had some insane and intense moments :rip:

 

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A cute and light-hearted video on COVID antibodies featuring Thai celebrities. (Also posted in the BL drama base thread.) In Thailand, having four shots is the norm, it seems. (They had to rely on Sinovac/Sinopharm/AZ in the beginning.)

 

Bonus: Jumpol Adulkittip0rn's cute face and his reactions to needles.

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1 hour ago, Jotham said:

 

The new Mao.

We love to see the CCP crash.

:gaycat4:

 

Poor Chinese citizen. Here come the next great famine with that kinda dumb stubborn anti-science leader.

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‚ÄúPandemic of the unvaccinated‚ÄĚ indeed

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Glad this sh*t is over in many countries including ours. :alexz:

 

Sorry for those who are still having surges and lockdowns. :heart:

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It's going to take at least another month to get back to zero :skull: I don't think the people in Shanghai are going to bear that long

 

 

 

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5 hours ago, frenchyisback said:

 

The new Mao.

We love to see the CCP crash.

:gaycat4:

 

Poor Chinese citizen. Here come the next great famine with that kinda dumb stubborn anti-science leader.

i wonder how they are gonna do with the "permanent COVID positive" cases there :cm:

 

Summary:

  • Only confirmation from isolation centre can be considered as proof for recovery. No self-testing is allowed and no test will be offered to people who refuse to go to "isolation centre".
  • If a person refuses to go to "isolation centre" even¬†test results are negative, that person¬†will be considered¬†as POSITIVE case permanently and the health code will forever be shown as POSITIVE
  • The whole community / residential area¬†will be locked down if any one of the resident refuses to go to "isolation centre"

 

Edited by truthteller
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Quote

Those who received the Sinovac vaccine were 4.59 times more likely to have severe COVID-19 compared to those who received the Pfizer-BioNTech vaccine. They were also 2.37 times more likely to be infected, compared to those who took the Pfizer-BioNTech vaccine.

 

The findings also suggest that the Moderna vaccine is more effective at preventing severe disease than the Pfizer-BioNTech vaccine.

 

Those who took the Moderna were found to be less than half (0.42) times as likely to develop severe COVID-19 than Pfizer-BioNTech recipients, and they are also less likely to be infected.

 

Citing a report from the US Centers for Disease Control and Prevention, the higher effectiveness of the Moderna vaccine was likely because of the higher mRNA content in the Moderna vaccine and longer time interval between the jabs.

 

Quote

A total of 107,220 of those vaccinated were confirmed by polymerase chain reaction (PCR) tests to have COVID-19 over the study period, and 644 developed severe disease.

 

While the study was based on ‚Äúcomprehensive national data‚ÄĚ, the team said there were ‚Äúseveral limitations‚ÄĚ.

This included the ‚Äúresidual confounding‚ÄĚ from comorbidities as well as factors that influence a person‚Äôs choice of vaccine or risk of exposure. There were also asymptomatic cases who did not see a doctor and were not recorded as cases.

 

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My last post before the forum reset was on the Dept Head of UCSF saying for the U.S. to get mRNA boosters every 2 months until better boosters are developed for Omicron/BA2 and we get a higher Paxlovid supply. I'd try it if the pharmacy allowed it but they've been strict with attempts from friends I know :coffee2: 

 

Also Chise already clarified that XE is NOT a new VOC. Of course it's still worth posting about and monitoring, but it's important to clarify that. 

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