ClashAndBurn Posted July 22, 2022 Posted July 22, 2022 Ron Klain and Leana Wen are absolute sociopaths. Joe Biden, who has unmatched access to quality health care, contracting COVID should not be a teaching movement that it is okay for everyone else to get it when COVID has long-lasting/permanent effects on lung capacity, brain function, etc.
Vermillion Posted July 22, 2022 Posted July 22, 2022 4 hours ago, ClashAndBurn said: Ron Klain and Leana Wen are absolute sociopaths. Joe Biden, who has unmatched access to quality health care, contracting COVID should not be a teaching movement that it is okay for everyone else to get it when COVID has long-lasting/permanent effects on lung capacity, brain function, etc. Leana specifically is finally getting some pushback in the press. Def worth a re-post
ClashAndBurn Posted July 23, 2022 Posted July 23, 2022 50 minutes ago, Espresso said: Leana specifically is finally getting some pushback in the press. Def worth a re-post Ngl, I was expecting some pushback here knowing how resistant people are to the idea of long COVID actually being a thing
Genius1111 Posted July 23, 2022 Author Posted July 23, 2022 1 hour ago, Espresso said: She posted this factsheet in her reply.
Vermillion Posted July 23, 2022 Posted July 23, 2022 Japan never really left masking culturally, and given their high density it's a stark warning for this fall and BA.5. I'm not surprised, I just hope it won't be ignored again but I should expect it will.
Vermillion Posted July 24, 2022 Posted July 24, 2022 5 hours ago, supertiffany said: so BA.5 is different from deltacron?? The short answer is yes. Some similarities though. A lot of ground to cover here, I took bits from much longer articles. Just read below. From Fortune, posted on July 12: Relatively new COVID-19 subvariant BA.5 takes some of Omicron’s worst traits—transmissibility and immune evasion—to a new level. But it also combines them with a penchant for affecting the lungs reminiscent of the Delta variant that hit the U.S last summer and fall, according to two recent studies. In the case of Delta, COVID tended to accumulate in and affect the lungs, potentially resulting in more severe disease. Until recently, a silver lining of Omicron has been its tendency to instead accumulate in the upper respiratory tract, causing symptoms more similar to a cold or the flu. BA.5 is different, according to a study published June 10 on medRxiv, a Yale– and British Medical Journal–affiliated website that publishes studies not yet certified by peer review. Recent reports show BA.5 shifting back to the lower respiratory tract—at least in animal models—“with a potential increase in disease severity and infection within lung tissue,” researchers from Australia’s Kirby Institute wrote. They referenced another May preprint study that found BA.5 and close relative BA.4 replicate more efficiently in the alveoli of human lungs than so-called stealth Omicron, BA.2. LINK From MedPageToday, posted on June 6: As with other Omicron variants, BA.4 and BA.5 symptoms are generally mild, and may include fever, malaise, and loss of smell, although the prevalence of long-term symptoms (long COVID) is still being evaluated. Serious illness is rare but possible, especially in the unvaccinated. Variant Survivability Variant survivability also involves testing evasion, vaccine evasion, and response to therapeutics. Duration and degree of viral shedding is important, as is surviving longer in the air or moving more readily through it. Possibly even more important is the percentage of infected people who become asymptomatic silent shedders, and the length of the incubation period, as this provides more time to infect more people without detection. All of these are key ingredients of COVID-19 variant transmissibility. The incubation of the newer variants seems to be slightly shorter (2 to 3 days). The bottom line is that BA.4 and BA.5 are very highly transmissible, cause little severe disease, and are responsive to boosters (although protection wanes), monoclonal antibodies, and antivirals. Unfortunately, both BA.4 and BA.5 are capable of escaping immune protection induced by infection with earlier Omicron and other prior variants, earning them the term "stealth" viruses. The unvaccinated are even less likely to be protected against symptomatic infection with BA.4 or BA.5. Sera from vaccinated individuals performed better in in vitro studies done thus far, but protection derived from currently available vaccines wanes over time. Fortunately, the third COVID vaccine booster dose slows down infection, spread, and serious disease from older variants. The effect of a third and fourth dose on BA.4 and BA.5 is still being evaluated. A universal Omicron vaccine is in development, but the efficacy is thus far unknown. Rapid Mutation Why are all these mutations happening so fast? BA.4 and BA.5 seem to undergo occasional mutational "sprints," mutating as much as four times faster than the normal Omicron mutation rate. More mutations can lead to more transmission, more severe disease, or evasion of the immune response -- much like flu's mutations. This may explain not only the rapid spread but also the non-linear spread, as in superspreader events where many get infected but some don't. There's also been genome swap between BA.1 and BA.2, and between Delta and Omicron in a single patient, as in the XE and "Deltacron" strains, respectively. BA.2.12.1 also seems to share properties with Delta. This exchange is also likely to be identified with BA.4 and BA.5. LINK
blaggot Posted July 24, 2022 Posted July 24, 2022 just tested positive for the first time ever ******* annoying
Jotham Posted July 24, 2022 Posted July 24, 2022 12 hours ago, Genius1111 said: I feel like this is a good indicator for how COVID will be for the Northern Hemisphere in the winter.
Lose My Breath Posted July 24, 2022 Posted July 24, 2022 Seems like it's only really infecting those who haven't had it before. I'm not sure that I know anyone other than a single person who has had B.a5 that had omicron since it was a thing. Do you guys know of any that were sick in January and later, that have been reinfected with this?
Vermillion Posted July 24, 2022 Posted July 24, 2022 1 hour ago, Lose My Breath said: Seems like it's only really infecting those who haven't had it before. I'm not sure that I know anyone other than a single person who has had B.a5 that had omicron since it was a thing. Do you guys know of any that were sick in January and later, that have been reinfected with this? I know three people personally that have been reinfected, including one person that had Omicron and recovered then got BA4 weeks ago and now despite testing negative still hasn't recovered.
Jotham Posted July 25, 2022 Posted July 25, 2022 Hopefully this is true. So far, the only person I know who got reinfected with BA.5 had Delta, I don't know anyone yet who had Omicron and got reinfected with BA.5. I'm still being cautious though and I got infected right before Easter.
Kamil24 Posted July 25, 2022 Posted July 25, 2022 Also true for me, my friends that have Covid right now are the ones that never had it before.
Virtual_Insanity Posted July 25, 2022 Posted July 25, 2022 I tested positive on Saturday, having managed to evade it for like 2.5 years lol. Oh well, I guess its gonna catch most people at some point. I know some who have had it three or four times at this stage so I cant complain too much. First three days were pretty rough, now on Day 4 and things are a bit better although still feel very meh. Fully vaccinated incl booster so if this is the mild version i definitely would not have wanted to get the unmild earlier version pre vaccine.
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